来源：风湿病与关节炎,2020,9（5）:26-31,40.

针灸治疗膝骨关节炎疗效及安全性的Meta分析（循证研究）

范梦梦¹，范仪铭²，李　峰²，刘　源²，郭珈宜²

　　【摘　要】目的：系统评价针灸治疗膝骨关节炎临床疗效和安全性。方法：计算机检索中国知网（CNKI）、万方、维普（VIP）、PubMed、Cochrane Library等数据库中有关针灸治疗膝骨关节炎的随机对照试验（RCT）文献，检索时间为2017年1月1日至2019年10月29日；并采用Review Manager 5.3软件对纳入的文献进行Meta分析。结果：共纳入23篇文献，总计1844例患者，试验组928例，对照组916例。Meta分析结果显示，在改善总有效率（OR = 3.48，95%CI = ［2.55，4.76］，P < 0.000 01），VAS评分（MD = -2.27，95%CI = ［-2.87，-1.67］，P < 0.000 01），WOMAC评分（MD = -14.55，95%CI = ［-18.67，-10.43］，P < 0.000 01）等方面，试验组优于对照组。结论：针灸治疗膝骨关节炎具有明显的优势。

　　【关键词】　骨关节炎，膝；温针灸；针刺；Meta分析

Meta-analysis for the Efficacy and Safety of Acupuncture and Moxibustion in the Treatment of Knee Osteoarthritis

FAN Meng-meng,FAN Yi-ming,LI Feng,LIU Yuan,GUO Jia-yi

　　【ABSTRACT】Objective:To systematically evaluate the clinical efficacy and safety of acupuncture and moxibustion in the treatment of knee osteoarthritis.Methods:Literature on randomized controlled trials of treating knee osteoarthritis with acupuncture and moxibustion was retrieved from databases such as CNKI,Wanfang,VIP,PubMed and Cochrane Library.The retrieval time was from January 1,2017 to October 29,2019.A meta-analysis was made for the literature by software Review Manager 5.3.Results:A total of 1844 patients（928 in the experiment group and 916 in the control group）were included in 23 articles.Meta-analysis showed that the experiment group was better than the control group in improving the total effective rate （OR = 3.48,95%CI = ［2.55,4.76］,P < 0.000 01）,VAS score（MD = -2.27,95%CI =［-2.87,-1.67］,P < 0.000 01）,WOMAC score（MD = -14.55,95%CI = ［-18.67,-10.43］,P < 0.000 01）.Conclusion:Acupuncture and moxibustion have distinct advantages in the treatment of knee osteoarthritis.

　　【Keywords】 osteoarthritis,knee;warm acupuncture and moxibustion;acupuncture;meta-analysis