来源：风湿病与关节炎,2019,8（8）:25-29.

基于中医传承辅助平台探讨当代中医治疗湿热证型结节性红斑内服汤剂的组方用药规律（文献研究）

甘元伟¹，梁　江^2,3，郑　腾¹，徐　宇¹，孔德忠¹

　　【摘　要】目的：分析中药内服汤剂治疗湿热证型结节性红斑的组方用药规律。方法：计算机检索中国知网、万方、维普等数据库中治疗湿热证型结节性红斑的文献，收入有效处方，并录入中医传承辅助平台（v2.5）中，采用关联规则、复杂系统熵聚类等无监督数据挖掘方法统计用药频次、药物归经、组方规律、新处方。结果：共输入56首处方，涉及151味中药，其中用药频次≥20次的有11味，用药归经频次较高的是肝经、心经、脾经，并得到常用核心组合12个，关联规则20条，发现新方7首。结论：部分学者和医家治疗湿热证型结节性红斑是以四妙散为基础的方药，以凉血活血、解毒除湿为主，可明确其治疗湿热证型结节性红斑的用药规律。

　　【关键词】　结节性红斑；湿热证型；中医传承辅助平台；用药规律；四妙散；内服汤剂

On the Prescription and Medication Law of Chinese Medicinal Decoction in Treating Nodular Erythema of Damp-heat Syndrome based on the TCM Inheritance and Assistance Platform

GAN Yuan-wei,LIANG Jiang,ZHENG Teng,XU Yu,KONG De-zhong

　　【ABSTRACT】Objective:To analyze the prescription and medication rule of Chinese medicinal decoction in treating nodular erythema of damp-heat syndrome.Methods:Literature on the treatment of nodular erythema with damp-heat syndrome was retrieved from databases of CNKI,Wanfang and Vip.Effective prescriptions were included in the TCM Inheritance and Assistance Platform（v2.5）.Unsupervised data mining methods such as association rules and complex system entropy clustering were used to count up the frequency of medication,meridian tropism,prescription laws and new prescriptions.Results:Fifty-six prescriptions involving 151 Chinese medicinals were inputted,of which 11 medicinals were used more than 20 times.The liver,heart and spleen meridians were more frequently targeted for meridian tropism.Twelve common core combinations and 20 association rules were obtained,and 7 new prescriptions were found.Conclusion:Most scholars and physicians treat nodular erythema of damp-heat syndrome with Simiao San（四妙散）as the basic prescription for cooling blood,promoting blood circulation,detoxification and dehumidification,which can clarify the medication rule of treating nodular erythema of damp-heat syndrome.

　　【Keywords】 nodular erythema;damp-heat syndrome;TCM Inheritance and Assistance Platform;medication law;Simiao San（四妙散）;decoction