来源：风湿病与关节炎,2019,8（7）:20-21,46.

379例强直性脊柱炎患者不同病程与性情急躁易怒患病率关系研究（临床研究）

杨林江¹，陈永前¹，娄玉钤¹，张秀甜²

　　【摘　要】目的：探讨强直性脊柱炎患者不同病程与性情急躁易怒患病率的关系，为“虚邪瘀”理论辨证治疗强直性脊柱炎提供依据。方法：提取河南风湿病医院强直性脊柱炎数据库相关资料，运用Pearson分析患者不同病程与性情急躁易怒患病率的关系。结果：379例强直性脊柱炎患者的平均年龄为（31.29±9.81）岁，按病程的长短分为3组：0～ < 36个月组、36～< 120个月组、≥120个月组。3组性情急躁易怒患病率分别为49.25%、48.67%、52.47%，男、女性情急躁易怒患病率分别为45.69%、72.73%。强直性脊柱炎患者不同病程与性情急躁易怒患病率无相关性（r = 0.030，P = 0.566）。结论：强直性脊柱炎患者病程长短与性情急躁易怒患病率无相关性；始终应该注重对强直性脊柱炎患者尤其是女性患者性情急躁易怒的治疗。

　　【关键词】　脊柱炎，强直性；性情急躁易怒；病程；虚邪瘀；HFAS数据库

Study on the Relationship Between the Duration of Ankylosing Spondylitis and the Prevalence of Irritability in 379 Cases

YANG Lin-jiang,CHEN Yong-qian,LOU Yu-qian,ZHANG Xiu-tian

　　【ABSTRACT】Objective:To explore the relationship between the different duration of ankylosing spondylitis and the prevalence of irritability,and to provide evidence for TCM syndrome differentiation and treatment of ankylosing spondylitis based on the theory of "deficiency,pathogen and stasis".Methods:The data of ankylosing spondylitis were extracted from the database of Henan Rheumatism Hospital,analyzing the relationship between the different courses of disease and the prevalence of irritability with Pearson.Results:The average age of 379 patients with ankylosing spondylitis was（31.29±9.81）years old.They were divided into three groups according to the course of disease:0～< 36-month group,36～< 120-month group and ≥120-month group.The prevalence rates of irritability in the three groups were 49.25%,48.67% and 52.47% respectively.The prevalence rates of irritability of men and women were 45.69% and 72.73% respectively.There was no correlation between the duration of ankylosing spondylitis and the prevalence of irritability（r = 0.030,P = 0.566）.Conclusion:There is no correlation between the duration of ankylosing spondylitis and the prevalence of irritability.Patients with ankylosing spondylitis,especially female patients,should always pay attention to the treatment of irritability.

　　【Keywords】 spondylitis,ankylosing;irritability;duration of disease;deficiency,pathogen and stasis;HFAS database