来源：风湿病与关节炎,2022,11（5）:21-25,36.

1017例痛风中医证候学调查研究分析（调查研究）

狄朋桃¹，王兴强¹，朱婉华²，张　玲³，靖卫霞⁴，张　明⁵，区培英⁶，章丽萍⁷，秦天楠⁸，汪学良⁹，赵钟文¹⁰，董秋梅¹¹，镇东鑫¹²，曹文萍¹³，张丽秀¹⁴，和智勇¹⁵，李学英¹⁶，胡俊桥¹⁷，张国峰¹⁸，曾　慧¹⁹，刘春丽²⁰，赵　博²¹，韦欧林²²，张　娴²³，彭江云¹

　　【摘　要】目的：调查和分析当前痛风发病情况和中医证候分布规律。方法：收集2019年1月至2022年1月云南省中医医院、南通良春中医医院等23家医院的1017例痛风患者，分析痛风患者基本情况、中医证候分布规律，中医证候在年龄、病情分期、血脂、血尿酸等方面的分布情况。结果：湿热蕴结证是痛风患者主要的中医证候，占70.21%。湿热蕴结证、寒湿痹阻证、痰瘀痹阻证均以急性期为主，分别占61.62%、54.65%、45.36%。脾虚湿阻证及肝肾阴虚证多见于间歇期及慢性期分别占46.81%和46.15%。不同证候年龄分布比较，差异有统计学意义（P < 0.01）；不同证候患者之间血尿酸水平比较，差异有统计学意义（P < 0.05）。结论：痛风发病年龄呈现年轻化趋势，中医证候分布与患者年龄、部分伴发疾病和血尿酸水平存在明显差异；痛风不同时期、证候分布也不相同。可为痛风辨证论治、规范治疗提供参考依据。

　　【关键词】　痛风；中医证候；分布规律；流行病学；调查研究

Investigation and Analysis of TCM Syndromes of 1017 Cases of Gout

DI Peng-tao,WANG Xing-qiang,ZHU Wan-hua,ZHANG Ling,JING Wei-xia,ZHANG Ming,QU Pei-ying,ZHANG Li-ping,QIN Tian-nan,WANG Xue-liang,ZHAO Zhong-wen,DONG Qiu-mei,ZHEN Dong-xin,CAO Wen-ping,ZHANG Li-xiu,HE Zhi-yong,LI Xue-ying,HU Jun-qiao,ZHANG Guo-feng,ZENG Hui,LIU Chun-li,ZHAO Bo,WEI Ou-lin,ZHANG Xian,PENG Jiang-yun

　　【ABSTRACT】Objective:To investigate and analyze the current incidence and TCM syndrome distribution of gout.Methods:1,017 patients with gout treated in 23 hospitals including Yunnan Provincial Hosoital of Traditional Chinese Medicine and Nantong Liangchun Hospital of Traditional Chinese Medicine from January 2019 to January 2022 were collected to analyze the basic condition,the distribution law of TCM syndromes,and the distributions of TCM syndromes in age,disease stage,blood lipid and blood uric acid.Results:Dampness heat accumulation syndrome is the main TCM syndrome of gout patients,Accounting for 70.21%.Dampness heat accumulation syndrome,cold dampness obstruction syndrome and phlegm stasis obstruction syndrome are mainly in acute stage,61.62%,54.65%and 45.36% respectively.Spleen deficiency and dampness obstruction syndrome and liver and kidney yin deficiency syndrome are mostly in intermittent stage and chronic stage,46.81% and 46.15% respectively.The age distribution difference of different syndromes is statistically significant（P < 0.05）,and there are significant differences in blood uric acid level among patients with different syndromes（P < 0.05）.Conclusion:The age of onset of gout shows a younger trend.There are significant differences between the distribution of TCM syndromes and the age of patients,some concomitant diseases and the level of blood uric acid.The distribution of syndromes is also different in different periods of gout,which can provide a reference for syndrome differentiation and treatment of gout and standardized treatment.

　　【Keywords】gout;TCM syndrome;distribution law;epidemiology;investigation and research